Provision of Protein G Sepharose and consumables

Description

Public Health England (PHE) is seeking to purchase affinity chromatography resin and associated columns to perform the depletion of IgG from human plasma at the 1-2 litre scale. These products are for the Pathogen Immunology Group within National Infection Service (NIS) Laboratories research department. PHE requires the Protein G Fast Flow Sepharose resin and columns to support the chromatography process developed in house. The requirement must meet the following mandatory specifications for Protein G Fast Flow Sepharose: - Must be available in 1L batches. - Must have proven track record for the depletion of IgG from human plasma at the 1-2 litre scale. - Must provide consistent depletion without activation of either the Complement cascade or the coagulation pathway at the 1-2 litre scale. - Resin must be of a pharmaceutical grade. The mandatory requirement also covers the provision of associated columns and consumables which will allow depletion of IgG and IgM using AKTA instruments. If you feel that you can meet the above requirements or would like more information, then please contact Aysel Sarzosa Aysel.Sarzosa@phe.gov.uk